Treatment of recurrent laryngeal papilloma by submucosal resection and the effect on prognosis / 临床耳鼻咽喉头颈外科杂志
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
; (24): 1873-1877, 2015.
Article
in Zh
| WPRIM
| ID: wpr-746906
Responsible library:
WPRO
ABSTRACT
OBJECTIVE@#To investigate the efficacy of submucosal resection by CO2 laser in the treatment of recurrent laryngeal papilloma and the effect on prognosis.@*METHOD@#A total of 11 patients diagnosed as recurrent laryngeal papilloma were included in this review. Papilloma was marked before operation and checked under fibro-laryngoscope. Papilloma was resected completely including the submucosal tissure with CO2 laser or microequipment. In widespread papilloma, false membrane in raw surface were cleared 7-10 days after operation. Surgical specimens (including membrane) were detected by routine pathology, HPV typing and immunohistochemical pathologic examination. The patients were checked once a month in the first 3 months after operation, and then once for every 3 months. Once the hoarseness and other symptoms aggravated or the disease was recurrent, the patients were treated immediately.@*RESULT@#HPV viral DNA was found in 10/11 cases, with HPV11 (7/11 cases) and HPV6 (3/11 cases). Cases with regards to follow-up, from 6 months to 1 year, 3 cases were followed up 1 year after operation, without recurrence. Five patients including 2 children were followed up 6 to 12 months after operation, without recurrence. Two children underwent 2 or 3 operations, were followed-up more than 6 months withouting recurrence.@*CONCLUSION@#Papilloma submucosal resection could decrease postoperative recurrence and is worth to be further investigated.
Full text:
1
Database:
WPRIM
Main subject:
Papilloma
/
Postoperative Period
/
Prognosis
/
Respiratory Tract Infections
/
General Surgery
/
Virology
/
Blood
/
DNA, Viral
/
Laryngeal Neoplasms
/
Laryngoscopes
Type of study:
Diagnostic_studies
/
Prognostic_studies
Limits:
Child
/
Humans
Language:
Zh
Journal:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
Year:
2015
Document type:
Article