Research progress of intracameral moxifloxacin in the prevention of bacterial endophthalmitis after cataract surgery / 中华实验眼科杂志
Chinese Journal of Experimental Ophthalmology
; (12): 461-465, 2022.
Article
in Zh
| WPRIM
| ID: wpr-931095
Responsible library:
WPRO
ABSTRACT
Postoperative endophthalmitis (POE) is a serious vision-threatening complication of cataract surgery, with an incidence rate of 0.033%-0.11% in China.In recent years, numerous retrospective studies and data analyses have reported that intracameral injection of antibiotics can effectively reduce the incidence of bacterial endophthalmitis, which commonly include cefuroxime, vancomycin and moxifloxacin.Globally, due to factors such as the availability, cost-effectiveness, and types of pathogens of POE, the drug choice varies to a large extent.Adverse events caused by antibiotics in the intracameral injection often occur, including macular edema, retinal vascular leakage, and uveitis caused by overdose of cefuroxime, and complications such as hemorrhagic retinal vasculitis obliterans due to vancomycin.Moxifloxacin, as a fourth-generation fluoroquinolone, has a significant effect on the prevention of bacterial endophthalmitis.Studies in the past five years related to moxifloxacin, and the significant advantages of moxifloxacin in the prevention of bacterial endophthalmitis, drug safety, duration of intracameral drug, and cost-effectiveness were summarized in this article.
Full text:
1
Database:
WPRIM
Type of study:
Observational_studies
Language:
Zh
Journal:
Chinese Journal of Experimental Ophthalmology
Year:
2022
Document type:
Article