The function of LncRNA-ATB in cancer
Clin. transl. oncol. (Print)
; 25(1): 1-9, ene. 2023.
Article
in En
| IBECS
| ID: ibc-215817
Responsible library:
ES1.1
Localization: ES15.1 - BNCS
ABSTRACT
Cancer as a progressive and complex disease is caused by early chromosomal changes and stimulated cellular transformation. Previous studies reported that long non-coding RNAs (lncRNAs) play pivotal roles in the initiation, maintenance, and progression of cancer cells. LncRNA activated by TGF-β (ATB) has been shown to be dysregulated in different types of cancer. Aberrant expression of lncRNA-ATB plays an important role in the progression of diverse malignancies. High expression of LncRNA-ATB is associated with cancer cell growth, proliferation, metastasis, and EMT. LncRNA-ATB by targeting various signaling pathways and microRNAs (miRNAs) can trigger cancer pathogenesis. Therefore, lncRNA-ATB can be a novel target for cancer prediction and diagnosis. In this review, we will focus on the function of lncRNA-ATB in various types of human cancers (AU)
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Collection:
06-national
/
ES
Database:
IBECS
Main subject:
MicroRNAs
/
RNA, Long Noncoding
/
Neoplasms
Limits:
Humans
Language:
En
Journal:
Clin. transl. oncol. (Print)
Year:
2023
Document type:
Article