Glioblastoma multiforme of the pineal region: case report
Arq. neuropsiquiatr
; 61(2B): 468-472, Jun. 2003. ilus, tab
Article
in En
| LILACS
| ID: lil-342796
Responsible library:
BR1.1
ABSTRACT
PURPOSE:
pineal region tumors are uncommon, and comprise more frequently three categories germ cell, parenchymal cell and glial tumors. Most pineal gliomas are low-grade astrocytomas. Glioblastoma multiforme, the most aggressive and common brain tumor, is extremely rare at this location with only few cases reported. CASE DESCRIPTION a 29-year-old woman with a two month history of headache, nuchal pain, fever, nausea and seizures and physical examination showing nuchal rigidity, generalized hypotony, hypotrophy and hyper-reflexia, Babinski sign and left VI cranial par palsy. CT scan examination revealed a ill-defined hypodense lesion at the pineal region with heterogeneous contrast enhancement. MRI showed a lesion at the pineal region infiltrating the right thalamic region. The patient underwent a right craniotomy with partial resection of the mass. The histological examination of paraffin-embedded material defined the diagnosis of glioblastoma multiforme. Post-operative radiotherapy was indicated but the patient refused the treatment and died two months afterwards.CONCLUSION:
in spite of its rarity at this location, glioblastoma multiforme should be considered in the differential diagnosis of aggressive lesions at the pineal region
Full text:
1
Collection:
01-internacional
Database:
LILACS
Main subject:
Pineal Gland
/
Brain Neoplasms
/
Glioblastoma
Limits:
Adult
/
Female
/
Humans
Language:
En
Journal:
Arq. neuropsiquiatr
Journal subject:
NEUROLOGIA
/
PSIQUIATRIA
Year:
2003
Document type:
Article
Affiliation country:
Brasil