Influência da testosterona na atividade macrofágica frente ao Trichophyton mentagrophytes / Influence of testosterone on macrophages activity cocultured with Trichophyton mentagrophytes
Hansen. int
; 33(1): 19-24, 2008. graf, ilus
Article
in Pt
| LILACS, SES-SP, SESSP-ILSLPROD, SES-SP, SESSP-ILSLACERVO, SES-SP
| ID: lil-523079
Responsible library:
BR191.1
RESUMO
O objetivo deste estudo foi avaliar a influência da testosterona sobre a atividade funcional de macrófagos murinos residentes frente ao Trichophyton mentagrophytes. Nas condições ensaiadas, a testosterona influenciou a liberação da H2O2 levando a redução da atividade microbicida dos macrófagos, facilitando o crescimento e diferenciação dos conídeos fagocitados.
ABSTRACT
The aim of this study was to evaluating the influence of male sexual hormone on activity of Swiss mice resident macrophages cocultured with Trichophyton mentagrophytes. In assayed conditions, testosterone influenced H2O2 release, leading to inhibition of killed macrophage activity in ingested conidia, facilitating its growth and differentiation inside macrophage.
Key words
Full text:
1
Collection:
01-internacional
Database:
LILACS
/
SES-SP
/
SESSP-ILSLACERVO
/
SESSP-ILSLPROD
Main subject:
Testosterone
/
Tinea
/
Macrophages, Peritoneal
Limits:
Animals
Language:
Pt
Journal:
Hansen. int
Journal subject:
Hansen¡ase
/
MEDICINA TROPICAL
Year:
2008
Document type:
Article
Affiliation country:
Brasil
Country of publication:
Brasil