Local low-dose urokinase treatment of acquired intracardiac thrombi in preterm infants.
Eur J Pediatr
; 158(9): 698-701, 1999 Sep.
Article
in En
| MEDLINE
| ID: mdl-10485298
ABSTRACT
We report three cases of intracardiac thrombi in preterm infants of very low birth weight, in whom local low-dose urokinase treatment achieved complete thrombolysis without any signs of systemic fibrinolytic activity or side-effects. This new treatment strategy seems to be safe, requires minimal monitoring of fibrinolytic activity, and may be a new option for thrombolysis in high-risk patients such as premature infants, patients recently operated on, and patients presenting with other contra-indications for systemic fibrinolytic therapy.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Thrombosis
/
Plasminogen Activators
/
Urokinase-Type Plasminogen Activator
/
Heart Diseases
/
Infant, Premature, Diseases
Type of study:
Diagnostic_studies
/
Etiology_studies
/
Risk_factors_studies
Limits:
Female
/
Humans
/
Male
/
Newborn
Language:
En
Journal:
Eur J Pediatr
Year:
1999
Document type:
Article
Affiliation country:
Suiza