Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.
Nature
; 402(6763): 761-8, 1999 Dec 16.
Article
in En
| MEDLINE
| ID: mdl-10617197
ABSTRACT
Arabidopsis thaliana (Arabidopsis) is unique among plant model organisms in having a small genome (130-140 Mb), excellent physical and genetic maps, and little repetitive DNA. Here we report the sequence of chromosome 2 from the Columbia ecotype in two gap-free assemblies (contigs) of 3.6 and 16 megabases (Mb). The latter represents the longest published stretch of uninterrupted DNA sequence assembled from any organism to date. Chromosome 2 represents 15% of the genome and encodes 4,037 genes, 49% of which have no predicted function. Roughly 250 tandem gene duplications were found in addition to large-scale duplications of about 0.5 and 4.5 Mb between chromosomes 2 and 1 and between chromosomes 2 and 4, respectively. Sequencing of nearly 2 Mb within the genetically defined centromere revealed a low density of recognizable genes, and a high density and diverse range of vestigial and presumably inactive mobile elements. More unexpected is what appears to be a recent insertion of a continuous stretch of 75% of the mitochondrial genome into chromosome 2.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Chromosome Mapping
/
Genes, Plant
/
Arabidopsis
/
DNA, Plant
Type of study:
Prognostic_studies
Language:
En
Journal:
Nature
Year:
1999
Document type:
Article
Affiliation country:
Estados Unidos