Successful treatment of Epstein-Barr virus-induced transverse myelitis with ganciclovir and cytomegalovirus hyperimmune globulin following unrelated bone marrow transplantation.
Bone Marrow Transplant
; 24(12): 1355-8, 1999 Dec.
Article
in En
| MEDLINE
| ID: mdl-10627648
ABSTRACT
We report a patient who developed Epstein-Barr virus (EBV)-induced transverse myelitis 19 months after unrelated bone marrow transplantation (BMT). The disease was diagnosed by physical examination, serologic determinations, EBV-specific polymerase chain reaction in peripheral blood lymphocytes and cerebrospinal fluid, and characteristic magnetic resonance imaging scan of the spine. The patient was treated with ganciclovir and cytomegalovirus (CMV) hyperimmune globulin. He gradually improved and recovered completely within 4 weeks. This case suggests that ganciclovir and CMV hyperimmune globulin appear to be effective for the treatment of EBV-induced transverse myelitis in immunocompromised patients following BMT.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Ganciclovir
/
Bone Marrow Transplantation
/
Immunization, Passive
/
Herpesvirus 4, Human
/
Myelitis, Transverse
Type of study:
Etiology_studies
Limits:
Adolescent
/
Humans
/
Male
Language:
En
Journal:
Bone Marrow Transplant
Journal subject:
TRANSPLANTE
Year:
1999
Document type:
Article
Affiliation country:
Alemania