Pituitary adenomas treated by microsurgery with or without Gamma Knife surgery: experience in 122 cases.
Stereotact Funct Neurosurg
; 72 Suppl 1: 125-31, 1999.
Article
in En
| MEDLINE
| ID: mdl-10681700
ABSTRACT
The clinical outcome of 122 patients with pituitary adenomas treated by microsurgery and/or Gamma Knife radiosurgery (GKRS) was analyzed to evaluate patient selection criteria and the role of GKRS. Sixty-six resections were performed in 59 patients. All tumors were macroadenomas, except for 5 ACTH-producing adenomas. Twenty-four of the 31 hypersecreting adenomas showed normal serum hormone values after treatment. Postoperative complications were rhinorrhea, cranial nerve palsies, and a small thalamic infarct. GKRS was performed on 18 of the operated patients because of residual tumors, mostly in the cavernous sinus. Thirty-five of the 63 patients treated by GKRS were followed for more than 2 years. All adenomas except 2 were stable or had decreased in size. Eleven of 17 functioning adenomas showed normal serum hormone values after treatment. It is concluded that tumors that compress the optic pathway should be removed and that residual tumors in the cavernous sinus are good indications for radiosurgery.
Search on Google
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pituitary Neoplasms
/
Adenoma
/
Radiosurgery
/
Microsurgery
Type of study:
Observational_studies
/
Prognostic_studies
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Stereotact Funct Neurosurg
Journal subject:
NEUROCIRURGIA
Year:
1999
Document type:
Article
Affiliation country:
Japón