Molecular modeling, affinity labeling, and site-directed mutagenesis define the key points of interaction between the ligand-binding domain of the vitamin D nuclear receptor and 1 alpha,25-dihydroxyvitamin D3.

Swamy, N; Xu, W; Paz, N; Hsieh, J C; Haussler, M R; Maalouf, G J; Mohr, S C; Ray, R

Swamy, N; Xu, W; Paz, N; Hsieh, J C; Haussler, M R; Maalouf, G J; Mohr, S C; Ray, R.

Affiliation

Swamy N; Bioorganic Chemistry and Structural Biology Group, Vitamin D Laboratory, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts 02118, USA.

Biochemistry ; 39(40): 12162-71, 2000 Oct 10.

Article in En | MEDLINE | ID: mdl-11015194

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Collection: 01-internacional Database: MEDLINE Main subject: Skatole / Calcifediol / Calcitriol / Affinity Labels / Models, Molecular / Mutagenesis, Site-Directed / Receptors, Calcitriol / Cholecalciferol Type of study: Prognostic_studies Limits: Humans Language: En Journal: Biochemistry Year: 2000 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos

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