Carcinoma/therapy; Pancreatic Neoplasms/therapy; Adjuvants, Immunologic/pharmacology; Adjuvants, Immunologic/therapeutic use; Antibodies, Monoclonal/therapeutic use; Antineoplastic Agents/therapeutic use; Bile; Biotransformation; Cancer Vaccines/therapeutic use; Carcinoma/drug therapy; Carcinoma/mortality; Clinical Trials as Topic; Cytochrome P-450 CYP2B1/administration & dosage; Cytochrome P-450 CYP2B1/genetics; Cytosine/analogs & derivatives; Cytosine/therapeutic use; DNA, Antisense/therapeutic use; Deoxycytidine/analogs & derivatives; Deoxycytidine/therapeutic use; Dioxolanes/therapeutic use; Endopeptidases/therapeutic use; Enzyme Inhibitors/pharmacology; Enzyme Inhibitors/therapeutic use; Genes, p53; Genes, ras; Genetic Therapy; Heat-Shock Proteins/immunology; Humans; Ifosfamide/pharmacokinetics; Multicenter Studies as Topic; Neoplasm Proteins/antagonists & inhibitors; Neoplastic Stem Cells/transplantation; Pancreatic Neoplasms/drug therapy; Pancreatic Neoplasms/mortality; Pectins/therapeutic use; Pilot Projects; Polyamines/therapeutic use; Prospective Studies; Prostheses and Implants; Sesquiterpenes/therapeutic use; Spiro Compounds/therapeutic use; Tissue Extracts; Topoisomerase I Inhibitors; Gemcitabine