Synthesis and SAR of 3- and 4-substituted quinolin-2-ones: discovery of mixed 5-HT(1B)/5-HT(2A) receptor antagonists.

McCort, G; Hoornaert, C; Aletru, M; Denys, C; Duclos, O; Cadilhac, C; Guilpain, E; Dellac, G; Janiak, P; Galzin, A M; Delahaye, M; Guilbert, F; O'Connor, S

McCort, G; Hoornaert, C; Aletru, M; Denys, C; Duclos, O; Cadilhac, C; Guilpain, E; Dellac, G; Janiak, P; Galzin, A M; Delahaye, M; Guilbert, F; O'Connor, S.

Affiliation

McCort G; Department of Cardiovascular/Thrombosis Medicinal Chemistry, Sanofi-Synthélabo Recherche, Chilly-Mazarin Cedex, France. gary.mccort@sanofi-synthelabo.com

Bioorg Med Chem ; 9(8): 2129-37, 2001 Aug.

Article in En | MEDLINE | ID: mdl-11504649

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Collection: 01-internacional Database: MEDLINE Main subject: Piperazines / Quinolines / Serotonin Antagonists / Receptors, Serotonin Limits: Animals Language: En Journal: Bioorg Med Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2001 Document type: Article Affiliation country: Francia Country of publication: Reino Unido

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