Hippocampal GABAergic interneurons: a physiological perspective.
Neurochem Res
; 26(8-9): 899-905, 2001 Sep.
Article
in En
| MEDLINE
| ID: mdl-11699941
ABSTRACT
Oscillations within and across neuronal systems are believed to serve various complex functions, such as perception, cognition, movement initiation, plasticity and memory. GABAergic interneurons and their inhibitory synapses play a major role in these oscillatory patterns. Networks of inhibitory interneurons impose a coordinated oscillatory "context" for the "content" carried by networks of principal cells. This hypothesis implies that GABAergic neuronal "supernetworks" may cooperatively entrain large populations of pyramidal cells throughout the forebrain. Experiments on hippocampal interneurons are reviewed and possible solutions for some of these complex functions are illustrated.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Gamma-Aminobutyric Acid
/
Hippocampus
/
Interneurons
Language:
En
Journal:
Neurochem Res
Year:
2001
Document type:
Article
Affiliation country:
Estados Unidos
Publication country:
EEUU
/
ESTADOS UNIDOS
/
ESTADOS UNIDOS DA AMERICA
/
EUA
/
UNITED STATES
/
UNITED STATES OF AMERICA
/
US
/
USA