[The effect of lidocaine on the bispectral index during anesthesia induction with propofol].
Masui
; 50(11): 1213-6, 2001 Nov.
Article
in Ja
| MEDLINE
| ID: mdl-11758326
ABSTRACT
We investigated the effect of premixing lidocaine with propofol on a bispectral index (BIS) during propofol infusion. We studied 40 adult patients given mixture of 1% propofol 20 ml with 2 ml of normal saline (control group) or 2% lidocaine (lidocaine group) infused at 2 ml.kg-1.hr-1 for 10 minutes. Heart rate, mean arterial pressure, and BIS were measured every minute. The addition of lidocaine to propofol reduced the incidence of injection pain from 85% to 10% but did not change the induction time. Propofol significantly decreased mean arterial pressure and BIS but there was no difference between the groups. In conclusion, premixing lidocaine with propofol reduces injection pain without affecting the hypnotic effect.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Propofol
/
Anesthetics, Intravenous
/
Anesthesia, Intravenous
/
Anesthetics, Local
/
Lidocaine
Type of study:
Clinical_trials
Limits:
Adult
/
Humans
/
Middle aged
Language:
Ja
Journal:
Masui
Year:
2001
Document type:
Article