[Biosynthesis and use of coproporphyrins and uroporphyrins and their metal complexes in immune analysis and diagnostic methods]. / Biosintez i primenenie koproporfirinov i uroporfirinov i ikh metallokompleksov v immnoanalize i diagnostike.
Prikl Biokhim Mikrobiol
; 37(6): 660-8, 2001.
Article
in Ru
| MEDLINE
| ID: mdl-11771318
ABSTRACT
Methods of synthesis of coproporphyrin and uroporphyrin by using bacteria of the genus Arthrobacter are proposed. Metal complexes of coproporphyrin and uroporphyrin with Pt, Pd, and Zn were synthesized. Their structures were identified by spectrophotometry, IR spectrometry, 1H-NMR, mass spectrometry, and HPLC. Data showing the possibility to use coproporphyrin III-metal complexes as luminophores for fluorescence detection of tumors. The current and prospective uses of metal complexes of water-soluble natural porphyrins in advanced immunofluorescence assays are discussed.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Uroporphyrins
/
Coproporphyrins
/
Fluorescent Dyes
/
Metalloporphyrins
/
Neoplasms
Type of study:
Diagnostic_studies
/
Prognostic_studies
Limits:
Animals
Language:
Ru
Journal:
Prikl Biokhim Mikrobiol
Year:
2001
Document type:
Article