Efficacy of a proprietary ibuprofen gel in soft tissue injuries: a randomised, double-blind, placebo-controlled study.
Int J Clin Pract
; 56(2): 102-6, 2002 Mar.
Article
in En
| MEDLINE
| ID: mdl-11926695
ABSTRACT
The efficacy of a novel, proprietary topical formulation of ibuprofen 5% gel (Ibugel) was evaluated in a placebo-controlled study in patients with soft tissue injuries. Patients received either active gel (n=40) or placebo gel (n=41) for a maximum of seven days. Pain and interference with physical activity were assessed daily using visual analogue scales. There was a significant difference (p<0.001) in favour of active treatment for the time to achieve clinically meaningful reduction in pain. By day 7, 75% of patients in the active gel group had a clinically meaningful reduction of pain compared with 39% of patients who received placebo. Despite differences between study centres, the data for interference with physical activity also showed an advantage for active treatment. By day 7, 79% of patients in the active gel group had a clinically meaningful reduction in interference with physical activity, compared with 44% of patients who received placebo.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pain
/
Anti-Inflammatory Agents, Non-Steroidal
/
Ibuprofen
/
Soft Tissue Injuries
Type of study:
Clinical_trials
Limits:
Adolescent
/
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Int J Clin Pract
Journal subject:
MEDICINA
Year:
2002
Document type:
Article
Affiliation country:
Reino Unido