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Investigation of potential bioisosteric replacements for the carboxyl groups of peptidomimetic inhibitors of protein tyrosine phosphatase 1B: identification of a tetrazole-containing inhibitor with cellular activity.
Liljebris, Charlotta; Larsen, Scott D; Ogg, Derek; Palazuk, Barbara J; Bleasdale, John E.
Affiliation
  • Liljebris C; Department of Medicinal Chemistry, Biovitrum AB, SE-751 82 Uppsala, Sweden. charlotta.liljrbris@biovitrum.com
J Med Chem ; 45(9): 1785-98, 2002 Apr 25.
Article in En | MEDLINE | ID: mdl-11960490
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Collection: 01-internacional Database: MEDLINE Main subject: Peptides / Propionates / Tetrazoles / Protein Tyrosine Phosphatases / Enzyme Inhibitors Type of study: Diagnostic_studies / Prognostic_studies Limits: Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2002 Document type: Article Affiliation country: Suecia
Search on Google
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Print
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PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Peptides / Propionates / Tetrazoles / Protein Tyrosine Phosphatases / Enzyme Inhibitors Type of study: Diagnostic_studies / Prognostic_studies Limits: Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2002 Document type: Article Affiliation country: Suecia