Improved viability of latissimus dorsi muscle grafts after electrical prestimulation.
Muscle Nerve
; 25(5): 679-684, 2002 May.
Article
in En
| MEDLINE
| ID: mdl-11994961
ABSTRACT
Surgical mobilization of the latissimus dorsi muscle (LDM) produces fiber degeneration, particularly in the distal part of the graft, that may compromise its function in clinical applications such as dynamic cardiomyoplasty. In five rats, the left LDM was stimulated continuously at 10 HZ. After 5 weeks, vessels perforating the chest wall were divided and the left LDM was mobilized as a pedicle graft based on the thoracodorsal artery. Twenty-four hours later, animals were killed and left and right LDMs were incubated with the vital stain nitroblue tetrazolium. Five control rats underwent a similar procedure without prestimulation. Mobilization of the LDM resulted in a loss of viability in the distal third of the muscle graft. This was reduced significantly by prestimulation (P = 0.006). Blood flow to the distal LDM graft is known to be augmented by electrical stimulation in situ before mobilization; the present results show that there is an associated enhancement of viability. The clinical implications of this finding are discussed.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Shoulder
/
Preoperative Care
/
Electric Stimulation Therapy
/
Muscle, Skeletal
Limits:
Animals
Language:
En
Journal:
Muscle Nerve
Year:
2002
Document type:
Article
Affiliation country:
Reino Unido
Publication country:
EEUU
/
ESTADOS UNIDOS
/
ESTADOS UNIDOS DA AMERICA
/
EUA
/
UNITED STATES
/
UNITED STATES OF AMERICA
/
US
/
USA