aph-1 and pen-2 are required for Notch pathway signaling, gamma-secretase cleavage of betaAPP, and presenilin protein accumulation.

Francis, Ross; McGrath, Garth; Zhang, Jianhuan; Ruddy, David A; Sym, Mary; Apfeld, Javier; Nicoll, Monique; Maxwell, Mark; Hai, Bing; Ellis, Michael C; Parks, Annette L; Xu, Wei; Li, Jinhe; Gurney, Mark; Myers, Richard L; Himes, Carol S; Hiebsch, Ronald; Ruble, Cara; Nye, Jeffrey S; Curtis, Daniel

Francis, Ross; McGrath, Garth; Zhang, Jianhuan; Ruddy, David A; Sym, Mary; Apfeld, Javier; Nicoll, Monique; Maxwell, Mark; Hai, Bing; Ellis, Michael C; Parks, Annette L; Xu, Wei; Li, Jinhe; Gurney, Mark; Myers, Richard L; Himes, Carol S; Hiebsch, Ronald; Ruble, Cara; Nye, Jeffrey S; Curtis, Daniel.

Affiliation

Francis R; Exelixis, Inc., South San Francisco, CA 94083, USA.

Dev Cell ; 3(1): 85-97, 2002 Jul.

Article in En | MEDLINE | ID: mdl-12110170

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Collection: 01-internacional Database: MEDLINE Main subject: Endopeptidases / Cell Membrane / Amyloid beta-Protein Precursor / Homeodomain Proteins / Caenorhabditis elegans Proteins / Membrane Proteins Language: En Journal: Dev Cell Journal subject: EMBRIOLOGIA Year: 2002 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos

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