Design, synthesis, and structure-activity relationship of 6-alkynylpyrimidines as potent adenosine kinase inhibitors.

Gomtsyan, Arthur; Didomenico, Stanley; Lee, Chih-Hung; Matulenko, Mark A; Kim, Ki; Kowaluk, Elizabeth A; Wismer, Carol T; Mikusa, Joe; Yu, Haixia; Kohlhaas, Kathy; Jarvis, Michael F; Bhagwat, Shripad S

Gomtsyan, Arthur; Didomenico, Stanley; Lee, Chih-Hung; Matulenko, Mark A; Kim, Ki; Kowaluk, Elizabeth A; Wismer, Carol T; Mikusa, Joe; Yu, Haixia; Kohlhaas, Kathy; Jarvis, Michael F; Bhagwat, Shripad S.

Affiliation

Gomtsyan A; Neuroscience Research, Global Pharmaceutical Products Division, Abbott Laboratories, 100 Abbott Park Road, Abbott Park, Illinois 60064, USA. authur.r.gomtsyan@abbott.com

J Med Chem ; 45(17): 3639-48, 2002 Aug 15.

Article in En | MEDLINE | ID: mdl-12166937

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Collection: 01-internacional Database: MEDLINE Main subject: Pyridines / Pyrimidines / Adenosine Kinase / Morpholines / Enzyme Inhibitors Limits: Animals / Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2002 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos

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