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Sirolimus oral absorption in rats is increased by ketoconazole but is not affected by D-alpha-tocopheryl poly(ethylene glycol 1000) succinate.
Wacher, Vincent J; Silverman, Jeffrey A; Wong, Susan; Tran-Tau, Paulina; Chan, Amy O; Chai, Anne; Yu, Xiang-Qing; O'Mahony, Daniel; Ramtoola, Zeibun.
Affiliation
  • Wacher VJ; AvMax Inc., South San Francisco, California 92009, USA. vwacher@worldnet.att.net
J Pharmacol Exp Ther ; 303(1): 308-13, 2002 Oct.
Article in En | MEDLINE | ID: mdl-12235265
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Collection: 01-internacional Database: MEDLINE Main subject: Vitamin E / Sirolimus / Intestinal Absorption / Ketoconazole Limits: Animals / Humans / Male Language: En Journal: J Pharmacol Exp Ther Year: 2002 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos
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Collection: 01-internacional Database: MEDLINE Main subject: Vitamin E / Sirolimus / Intestinal Absorption / Ketoconazole Limits: Animals / Humans / Male Language: En Journal: J Pharmacol Exp Ther Year: 2002 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos