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Development of a dual recombinant vaccine to protect small ruminants against peste-des-petits-ruminants virus and capripoxvirus infections.
Berhe, G; Minet, C; Le Goff, C; Barrett, T; Ngangnou, A; Grillet, C; Libeau, G; Fleming, M; Black, D N; Diallo, A.
Affiliation
  • Berhe G; Cirad, Programme Santé Animale, Campus International de Baillarguet, 34398 Montpellier Cedex 05, France.
J Virol ; 77(2): 1571-7, 2003 Jan.
Article in En | MEDLINE | ID: mdl-12502870
ABSTRACT
A recombinant capripoxvirus vaccine containing a cDNA of the peste-des-petits-ruminants virus (PPRV) fusion protein gene was constructed. A quick and efficient method was used to select a highly purified recombinant virus clone. A trial showed that a dose of this recombinant as low as 0.1 PFU protected goats against challenge with a virulent PPRV strain.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Viral Vaccines / Capripoxvirus / Poxviridae Infections / Peste-des-Petits-Ruminants / Animal Diseases Limits: Animals Language: En Journal: J Virol Year: 2003 Document type: Article Affiliation country: Francia
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Viral Vaccines / Capripoxvirus / Poxviridae Infections / Peste-des-Petits-Ruminants / Animal Diseases Limits: Animals Language: En Journal: J Virol Year: 2003 Document type: Article Affiliation country: Francia