Development of a dual recombinant vaccine to protect small ruminants against peste-des-petits-ruminants virus and capripoxvirus infections.
J Virol
; 77(2): 1571-7, 2003 Jan.
Article
in En
| MEDLINE
| ID: mdl-12502870
ABSTRACT
A recombinant capripoxvirus vaccine containing a cDNA of the peste-des-petits-ruminants virus (PPRV) fusion protein gene was constructed. A quick and efficient method was used to select a highly purified recombinant virus clone. A trial showed that a dose of this recombinant as low as 0.1 PFU protected goats against challenge with a virulent PPRV strain.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Viral Vaccines
/
Capripoxvirus
/
Poxviridae Infections
/
Peste-des-Petits-Ruminants
/
Animal Diseases
Limits:
Animals
Language:
En
Journal:
J Virol
Year:
2003
Document type:
Article
Affiliation country:
Francia