Therapeutic role of dual inhibitors of 5-LOX and COX, selective and non-selective non-steroidal anti-inflammatory drugs.
Ann Rheum Dis
; 62(6): 501-9, 2003 Jun.
Article
in En
| MEDLINE
| ID: mdl-12759283
ABSTRACT
Dual 5-LOX/COX inhibitors are potential new drugs to treat inflammation. They act by blocking the formation of both prostaglandins and leucotrienes but do not affect lipoxin formation. Such combined inhibition avoids some of the disadvantages of selective COX-2 inhibitors and spares the gatrointestinal mucosa.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Anti-Inflammatory Agents, Non-Steroidal
/
Lipoxygenase Inhibitors
/
Cyclooxygenase Inhibitors
Limits:
Humans
Language:
En
Journal:
Ann Rheum Dis
Year:
2003
Document type:
Article