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Synthetic triterpenoids activate a pathway for apoptosis in AML cells involving downregulation of FLIP and sensitization to TRAIL.
Suh, W-S; Kim, Y S; Schimmer, A D; Kitada, S; Minden, M; Andreeff, M; Suh, N; Sporn, M; Reed, J C.
Affiliation
  • Suh WS; The Burnham Institute, La Jolla, CA 92037, USA.
Leukemia ; 17(11): 2122-9, 2003 Nov.
Article in En | MEDLINE | ID: mdl-12931220
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Collection: 01-internacional Database: MEDLINE Main subject: Oleanolic Acid / Protease Inhibitors / Membrane Glycoproteins / Carrier Proteins / Gene Expression Regulation, Neoplastic / Tumor Necrosis Factor-alpha / Apoptosis / Intracellular Signaling Peptides and Proteins / Antineoplastic Agents Type of study: Prognostic_studies Limits: Humans Language: En Journal: Leukemia Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2003 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido
Search on Google
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Collection: 01-internacional Database: MEDLINE Main subject: Oleanolic Acid / Protease Inhibitors / Membrane Glycoproteins / Carrier Proteins / Gene Expression Regulation, Neoplastic / Tumor Necrosis Factor-alpha / Apoptosis / Intracellular Signaling Peptides and Proteins / Antineoplastic Agents Type of study: Prognostic_studies Limits: Humans Language: En Journal: Leukemia Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2003 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido