Serum TNF in patients with severe malaria treated by exchange transfusion.
Trop Med Parasitol
; 43(4): 285-6, 1992 Dec.
Article
in En
| MEDLINE
| ID: mdl-1293736
ABSTRACT
The authors report on three cases of severe P. falciparum malaria successfully treated by iv quinine and exchange transfusion. Serum concentrations of Tumor Necrosis Factor (TNF) were determined before and during treatment. After an initial decrease, serum levels of TNF remained markedly elevated during the first 48 hours despite exchange transfusion. Though exchange transfusion accelerates the elimination of parasites from the blood, it seems to have no immediate effects on reducing serum levels of cytokines such as TNF.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Quinine
/
Exchange Transfusion, Whole Blood
/
Tumor Necrosis Factor-alpha
/
Malaria, Falciparum
Limits:
Adult
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Trop Med Parasitol
Journal subject:
MEDICINA TROPICAL
/
PARASITOLOGIA
Year:
1992
Document type:
Article
Affiliation country:
Suiza