Adenosine diphosphate binding to sodium-plus-potassium ion-dependent adenosine triphosphatase. The role of lipid in the nucleotide-potassium ion interplay.
Biochem J
; 159(3): 815-7, 1976 Dec 01.
Article
in En
| MEDLINE
| ID: mdl-137721
ABSTRACT
Delipidated dogfish rectal-gland Na++K+-ATPase (Na++K+-dependent adenosine triphosphatase), almost devoid of hydrolytic activity, is able to bind about 2nmol of ADP/mg of protein. The "affinity" of delipidated enzyme for ADP is not affected by K+ in concentrations that greatly decrease the "affinity" of native Na++K+-ATPase. The K+-sensitivity of the ADP binding is in part restored by relipidation with dioleoyl phosphatidylcholine.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Adenosine Diphosphate
/
Adenosine Triphosphatases
/
Lipid Metabolism
Language:
En
Journal:
Biochem J
Year:
1976
Document type:
Article