Changes in immunological response in tonsillectomized children. II. Decreased cellular response.
Clin Otolaryngol Allied Sci
; 17(5): 380-2, 1992 Oct.
Article
in En
| MEDLINE
| ID: mdl-1458617
ABSTRACT
The immunological cellular response was studied in 22 children aged between 5 and 10 years. One week before and one month after tonsillectomy, the mitogenic response to phytohaemagglutinin (PHA), concanavalin (ConA) and pokeweed mitogen (PWM) was tested. Our results showed statistically significant decreases in stimulation index (SI) to PHA, ConA and PWM after tonsillectomy. This suggests that the tonsils may influence the cellular immune status in children. The higher level of preoperative activity in children with recurrent tonsillitis could be understood as the result of stimulation of lymphocytes by bacteria.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Palatine Tonsil
/
Tonsillectomy
/
T-Lymphocytes
Limits:
Child
/
Child, preschool
/
Humans
Language:
En
Journal:
Clin Otolaryngol Allied Sci
Year:
1992
Document type:
Article
Affiliation country:
España