[Movement disorders in childhood: classification and genetic update]. / Mouvements anormaux de l'enfant : classification et aspects génétiques.
Arch Pediatr
; 10(11): 994-1002, 2003 Nov.
Article
in Fr
| MEDLINE
| ID: mdl-14613695
Abnormal movements are not unusual in childhood. Recent genetic progresses provide a new approach of childhood movement disorders. Several loci have been identified in paroxysmal dyskinesia, or in Gilles de la Tourette syndrome. A gene has been cloned in Hallervorden-Spatz syndrome, and a gene has recently been implicated in benign hereditary chorea. Considerable advances concern the genetic of dystonic syndromes: several chromosomal localizations have been identified, and several genes have been cloned. Genetic advances allow nosographic reclassification of some entities and offer new molecular tools for a more appropriate diagnosis. The increasing wealth of genetic knowledge will provide further insight in the understanding of abnormal movement disorders in childhood.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Genetic Predisposition to Disease
/
Movement Disorders
Limits:
Child
/
Humans
Language:
Fr
Journal:
Arch Pediatr
Year:
2003
Document type:
Article
Affiliation country:
Francia
Country of publication:
Francia