Diagnosis of plasma cell leukaemia: findings of the UK NEQAS for Leucocyte Immunophenotyping scheme.
Clin Lab Haematol
; 26(1): 37-42, 2004 Feb.
Article
in En
| MEDLINE
| ID: mdl-14738436
ABSTRACT
The diagnosis of plasma cell leukaemia, a rare disorder with an aggressive clinical course and poor prognosis, is not always straightforward and may be dependent on the results of immunophenotyping. Samples from two cases of plasma cell leukaemia have been issued by the UK NEQAS for Leucocyte Immunophenotyping Scheme during the last 5 years and on each occasion a significant number of laboratories failed to make the correct diagnosis. The details of the two samples issued and the results of both surveys are presented. The data highlights the need to adhere to guidelines for immunophenotyping, with respect to using the correct antibody panels, the importance of data interpretation in conjunction with morphological appearance as well as the need to participate in external quality assurance schemes.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Leukemia, Plasma Cell
/
Immunophenotyping
/
Clinical Laboratory Techniques
/
Guideline Adherence
/
Leukocytes
Type of study:
Diagnostic_studies
/
Guideline
/
Prognostic_studies
/
Qualitative_research
Limits:
Female
/
Humans
/
Male
Language:
En
Journal:
Clin Lab Haematol
Year:
2004
Document type:
Article
Affiliation country:
Reino Unido