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Value of routine follow-up procedures for patients with stage I/II cervical cancer treated with combined surgery-radiation therapy.
Morice, P; Deyrolle, C; Rey, A; Atallah, D; Pautier, P; Camatte, S; Thoury, A; Lhomme, C; Haie-Meder, C; Castaigne, D.
Affiliation
  • Morice P; Department of Gynecologic Surgery, Institut Gustave Roussy, Villejuif, France. morice@igr.fr
Ann Oncol ; 15(2): 218-23, 2004 Feb.
Article in En | MEDLINE | ID: mdl-14760112
ABSTRACT

BACKGROUND:

The aim of this study was to determine the value of routine follow-up for the detection of recurrence in patients treated for cervical cancer. PATIENTS AND

METHODS:

From 1986 to 1998, 583 women with stage I and II cervical carcinoma were treated with combined surgery-radiation therapy. After treatment, follow-up was based on clinical examination, a systematic Pap smear and radiography (chest X-ray and abdomino-pelvic ultrasonography).

RESULTS:

Forty-five patients had recurrence observed with a delay > or = 6 months following the end of treatment. Thirty-eight patients had symptoms and seven were asymptomatic at the time of their recurrence. Among asymptomatic patients only two recurrences were diagnosed following routine examinations. Survival is similar in asymptomatic and symptomatic recurrent patients.

CONCLUSIONS:

In conclusion, follow-up of patients treated for cervical cancer based on routine Pap smears and systematic radiography does not permit earlier detection of recurrence and does not increase survival.
Subject(s)
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Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Squamous Cell / Adenocarcinoma / Uterine Cervical Neoplasms / Carcinoma, Adenosquamous / Neoplasm Recurrence, Local Type of study: Diagnostic_studies / Evaluation_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Middle aged Language: En Journal: Ann Oncol Journal subject: NEOPLASIAS Year: 2004 Document type: Article Affiliation country: Francia
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Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Squamous Cell / Adenocarcinoma / Uterine Cervical Neoplasms / Carcinoma, Adenosquamous / Neoplasm Recurrence, Local Type of study: Diagnostic_studies / Evaluation_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Middle aged Language: En Journal: Ann Oncol Journal subject: NEOPLASIAS Year: 2004 Document type: Article Affiliation country: Francia
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