Effect of fish oil on the fatty acid composition of human milk and maternal and infant erythrocytes.
Lipids
; 27(11): 863-9, 1992 Nov.
Article
in En
| MEDLINE
| ID: mdl-1491604
ABSTRACT
To examine the effect of fish oil supplementation on the fatty acid (FA) composition of human milk and maternal and infant erythrocytes, five lactating women were supplemented with 6 g of fish oil daily for 21 d. Usual maternal diets contained 1,147 mg of total n-3 FA, with 120 mg from very long-chain (> C18) n-3 FA. Supplementation increased dietary levels to 3,092 mg of total n-3 FA and 2,006 mg of very long-chain n-3 FA. Milk samples were collected daily, prior to fish oil ingestion, and at 4-h intervals on days 1, 7, 14 and 21. Milk n-3 FA content increased within 8 h and reached steady state levels within one week. The n-6 fatty acid content decreased. Erythrocyte eicosapentaenoic acid content increased from 0.24% to 1.4% (P < 0.01) in mothers and from 0.11% to 0.70% (P < 0.05) in infants. Docosapentaenoic acid increased from 1.4% to 2.2% (P < 0.05) in mothers and from 0.30% to 0.78% (P < 0.01) in infants. There was no significant change in docosahexaenoic acid or n-6 fatty acid content. Maternal platelet aggregation responses were variable. No differences in milk or plasma tocopherol levels were noted.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Dietary Fats, Unsaturated
/
Fish Oils
/
Erythrocytes
/
Fatty Acids
/
Milk, Human
Limits:
Female
/
Humans
/
Newborn
Language:
En
Journal:
Lipids
Year:
1992
Document type:
Article