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A novel DNA-dependent protein kinase inhibitor, NU7026, potentiates the cytotoxicity of topoisomerase II poisons used in the treatment of leukemia.
Willmore, Elaine; de Caux, Sarah; Sunter, Nicola J; Tilby, Michael J; Jackson, Graham H; Austin, Caroline A; Durkacz, Barbara W.
Affiliation
  • Willmore E; School of Cell and Molecular Biosciences, University of Newcastle-upon-Tyne Medical School, Newcastle-upon-Tyne NE2 4HH, United Kingdom.
Blood ; 103(12): 4659-65, 2004 Jun 15.
Article in En | MEDLINE | ID: mdl-15010369
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Collection: 01-internacional Database: MEDLINE Main subject: Morpholines / Chromones / Protein Serine-Threonine Kinases / DNA-Binding Proteins / Topoisomerase II Inhibitors / Antineoplastic Agents Type of study: Prognostic_studies Limits: Humans Language: En Journal: Blood Year: 2004 Document type: Article Affiliation country: Reino Unido Country of publication: Estados Unidos
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Collection: 01-internacional Database: MEDLINE Main subject: Morpholines / Chromones / Protein Serine-Threonine Kinases / DNA-Binding Proteins / Topoisomerase II Inhibitors / Antineoplastic Agents Type of study: Prognostic_studies Limits: Humans Language: En Journal: Blood Year: 2004 Document type: Article Affiliation country: Reino Unido Country of publication: Estados Unidos