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A patient with a VEGF and endostatin producing gastrointestinal autonomic nerve tumour.
Hansma, A H G; van Hensbergen, Y; Kuenen, B C; van Diest, P J; Hanemaaijer, R; Meijer, S; Pinedo, H M; Hoekman, K.
Affiliation
  • Hansma AH; Department of Medical Oncology, Vrije Universiteit Medical Centre, De Boelelaan 1117, 1007 MB Amsterdam, The Netherlands.
J Clin Pathol ; 57(5): 536-8, 2004 May.
Article in En | MEDLINE | ID: mdl-15113863
ABSTRACT
Tumour associated neovascularisation has been characterised as chaotic and insufficient. This report details the results of the analysis of angiogenic factors in tumour cyst fluid, pleural fluid, and blood from a patient with a gastrointestinal autonomic nerve tumour. The tumour produced vascular endothelial growth factor and endostatin in large quantities, which may explain the dysfunctional angiogenesis and tendency to bleeding seen in this tumour type.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peripheral Nervous System Neoplasms / Autonomic Nervous System Diseases / Endostatins / Vascular Endothelial Growth Factor A / Gastrointestinal Neoplasms / Neoplasm Proteins Limits: Adult / Female / Humans Language: En Journal: J Clin Pathol Year: 2004 Document type: Article Affiliation country: Países Bajos
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peripheral Nervous System Neoplasms / Autonomic Nervous System Diseases / Endostatins / Vascular Endothelial Growth Factor A / Gastrointestinal Neoplasms / Neoplasm Proteins Limits: Adult / Female / Humans Language: En Journal: J Clin Pathol Year: 2004 Document type: Article Affiliation country: Países Bajos