The relationship between aberrant methylation and survival in non-small-cell lung cancers.
Br J Cancer
; 91(4): 771-4, 2004 Aug 16.
Article
in En
| MEDLINE
| ID: mdl-15266335
ABSTRACT
The present study examined the relationship between methylation of five genes (p16(INK4a), RASSF1A, APC, RARbeta and CDH13) and patient survival in 351 cases of surgically resected lung cancers. While there was no relationship between the other genes and survival, p16(INK4a) methylation was significantly related to unfavourable prognosis in lung adenocarcinomas.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
DNA, Neoplasm
/
Adenocarcinoma
/
Carcinoma, Non-Small-Cell Lung
/
DNA Methylation
/
Genes, p16
/
Lung Neoplasms
Type of study:
Observational_studies
Limits:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Br J Cancer
Year:
2004
Document type:
Article
Affiliation country:
Estados Unidos