Clinical utility of unbound antiepileptic drug blood levels in the management of epilepsy.
Neurology
; 42(5): 988-90, 1992 May.
Article
in En
| MEDLINE
| ID: mdl-1579255
ABSTRACT
We tabulated all unbound and total antiepileptic blood levels collected in 13 months. According to strict criteria, 24% of phenytoin and 15% of valproate unbound blood levels but none of the carbamazepine unbound levels had clinical significance in the management of seizures or side effects. These data support frequent use of unbound phenytoin or valproate blood levels in the management of epilepsy.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Epilepsy
/
Anticonvulsants
Limits:
Humans
Language:
En
Journal:
Neurology
Year:
1992
Document type:
Article