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Somatic and germline mutation in GRIM-19, a dual function gene involved in mitochondrial metabolism and cell death, is linked to mitochondrion-rich (Hurthle cell) tumours of the thyroid.
Máximo, V; Botelho, T; Capela, J; Soares, P; Lima, J; Taveira, A; Amaro, T; Barbosa, A P; Preto, A; Harach, H R; Williams, D; Sobrinho-Simões, M.
Affiliation
  • Máximo V; IPATIMUP-Institute of Molecular Pathology and Immunology of the University of Porto, Rua Dr Roberto Frias s/n, 4200-465 Porto, Portugal.
Br J Cancer ; 92(10): 1892-8, 2005 May 23.
Article in En | MEDLINE | ID: mdl-15841082

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thyroid Neoplasms / Adenoma, Oxyphilic / Mitochondria / NADH, NADPH Oxidoreductases Type of study: Observational_studies / Prognostic_studies Limits: Adult / Humans / Middle aged Language: En Journal: Br J Cancer Year: 2005 Document type: Article Affiliation country: Portugal Country of publication: Reino Unido

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thyroid Neoplasms / Adenoma, Oxyphilic / Mitochondria / NADH, NADPH Oxidoreductases Type of study: Observational_studies / Prognostic_studies Limits: Adult / Humans / Middle aged Language: En Journal: Br J Cancer Year: 2005 Document type: Article Affiliation country: Portugal Country of publication: Reino Unido