FoldIndex: a simple tool to predict whether a given protein sequence is intrinsically unfolded.
Bioinformatics
; 21(16): 3435-8, 2005 Aug 15.
Article
in En
| MEDLINE
| ID: mdl-15955783
ABSTRACT
An easy-to-use, versatile and freely available graphic web server, FoldIndex is described it predicts if a given protein sequence is intrinsically unfolded implementing the algorithm of Uversky and co-workers, which is based on the average residue hydrophobicity and net charge of the sequence. FoldIndex has an error rate comparable to that of more sophisticated fold prediction methods. Sliding windows permit identification of large regions within a protein that possess folding propensities different from those of the whole protein.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Algorithms
/
User-Computer Interface
/
Software
/
Proteins
/
Models, Molecular
/
Sequence Alignment
/
Sequence Analysis, Protein
/
Models, Chemical
Type of study:
Prognostic_studies
/
Risk_factors_studies
Language:
En
Journal:
Bioinformatics
Journal subject:
INFORMATICA MEDICA
Year:
2005
Document type:
Article
Affiliation country:
Israel