Encephalomyelitis, Autoimmune, Experimental/genetics; Encephalomyelitis, Autoimmune, Experimental/immunology; Glycoproteins/administration & dosage; Glycoproteins/immunology; Peptide Fragments/administration & dosage; Peptide Fragments/immunology; Receptors, Tumor Necrosis Factor/deficiency; Receptors, Tumor Necrosis Factor/genetics; Amino Acid Sequence; Animals; CD4-Positive T-Lymphocytes/immunology; CD4-Positive T-Lymphocytes/metabolism; CD4-Positive T-Lymphocytes/pathology; CD4-Positive T-Lymphocytes/transplantation; Cell Membrane/immunology; Cell Membrane/metabolism; Cell Membrane/pathology; Cell Movement/genetics; Cell Movement/immunology; Cell Proliferation; Cells, Cultured; Down-Regulation/genetics; Down-Regulation/immunology; Encephalomyelitis, Autoimmune, Experimental/pathology; Epitopes, T-Lymphocyte/immunology; Female; Immunity, Innate/genetics; Immunization, Passive; Integrin alpha4beta1/antagonists & inhibitors; Integrin alpha4beta1/biosynthesis; Interleukin-4/biosynthesis; Lymphocyte Activation/genetics; Lymphocyte Count; Mice; Mice, Knockout; Molecular Sequence Data; Myelin-Oligodendrocyte Glycoprotein; Receptors, Tumor Necrosis Factor/physiology; Spleen/cytology; Spleen/immunology; Spleen/metabolism; Up-Regulation/genetics; Up-Regulation/immunology