Cyclic urea derivatives as potent NK1 selective antagonists. Part II: Effects of fluoro and benzylic methyl substitutions.

Shue, Ho-Jane; Chen, Xiao; Schwerdt, John H; Paliwal, Sunil; Blythin, David J; Lin, Ling; Gu, Danlin; Wang, Cheng; Reichard, Gregory A; Wang, Hongwu; Piwinski, John J; Duffy, Ruth A; Lachowicz, Jean E; Coffin, Vicki L; Nomeir, Amin A; Morgan, Cynthia A; Varty, Geoffrey B; Shih, Neng-Yang

Shue, Ho-Jane; Chen, Xiao; Schwerdt, John H; Paliwal, Sunil; Blythin, David J; Lin, Ling; Gu, Danlin; Wang, Cheng; Reichard, Gregory A; Wang, Hongwu; Piwinski, John J; Duffy, Ruth A; Lachowicz, Jean E; Coffin, Vicki L; Nomeir, Amin A; Morgan, Cynthia A; Varty, Geoffrey B; Shih, Neng-Yang.

Affiliation

Shue HJ; Chemical Research Department, Schering-Plough Research Institute, 2015 Galloping Hill Road, Kenilworth, NJ 07033, USA.

Bioorg Med Chem Lett ; 16(4): 1065-9, 2006 Feb 15.

Article in En | MEDLINE | ID: mdl-16290143

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Collection: 01-internacional Database: MEDLINE Main subject: Anti-Anxiety Agents / Urea / Neurokinin-1 Receptor Antagonists Limits: Animals Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2006 Document type: Article Affiliation country: Estados Unidos

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