Dynamic interleaved 1H/31P STEAM MRS at 3 Tesla using a pneumatic force-controlled plantar flexion exercise rig.
MAGMA
; 18(5): 257-62, 2005 Nov.
Article
in En
| MEDLINE
| ID: mdl-16320091
ABSTRACT
OBJECTIVE:
To develop a measurement method for interleaved acquisition of 1H and 31 STEAM localised spectra of exercising human calf muscle. MATERIALS ANDMETHODS:
A non-magnetic exercise rig with a pneumatic piston and sensors for force and pedal angle was constructed to enable plantar flexion measured in the 3 T MR scanner, which holds the dual tuned (1H ,31P) surface coil used for signal transmission and reception.RESULTS:
(31) spectra acquired in interleaved mode benefit from higher Signal to noise ratio (factor of 1.34 +/-0.06 for PCr) compared to standard acquisition due to the Nuclear Overhauser effect and substantial PCr/P(i) changes during exercise can be observed in 31P spectra. 1H spectral quality is equal to that in single mode experiments and allows Cr2 changes to be monitored.CONCLUSION:
The feasibility of dynamic interleaved localised 1H and 31P spectroscopy during plantar flexion exercise has been demonstrated using a custom-built pneumatic system for muscle activation. This opens the possibility of studying the dynamics of metabolism with multi nuclear MRS in a single run.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Phosphates
/
Magnetic Resonance Spectroscopy
/
Muscle, Skeletal
/
Exercise Test
/
Muscle Contraction
/
Myoglobin
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
En
Journal:
MAGMA
Journal subject:
DIAGNOSTICO POR IMAGEM
Year:
2005
Document type:
Article
Affiliation country:
Austria