Beta-substituted cyclohexanecarboxamide: a nonpeptidic framework for the design of potent inhibitors of cathepsin K.

Crane, Sheldon N; Black, W Cameron; Palmer, James T; Davis, Dana E; Setti, Eduardo; Robichaud, Joel; Paquet, Julie; Oballa, Renata M; Bayly, Christopher I; McKay, Daniel J; Somoza, John R; Chauret, Natalie; Seto, Carmai; Scheigetz, John; Wesolowski, Greg; Massé, Frederic; Desmarais, Sylvie; Ouellet, Marc

Crane, Sheldon N; Black, W Cameron; Palmer, James T; Davis, Dana E; Setti, Eduardo; Robichaud, Joel; Paquet, Julie; Oballa, Renata M; Bayly, Christopher I; McKay, Daniel J; Somoza, John R; Chauret, Natalie; Seto, Carmai; Scheigetz, John; Wesolowski, Greg; Massé, Frederic; Desmarais, Sylvie; Ouellet, Marc.

Affiliation

Crane SN; Merck Frosst Centre for Therapeutic Research, 16711 TransCanada Highway, Kirkland, Quebec, Canada, H9H 3L1. sheldon_crane@merck.com

J Med Chem ; 49(3): 1066-79, 2006 Feb 09.

Article in En | MEDLINE | ID: mdl-16451072

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Collection: 01-internacional Database: MEDLINE Main subject: Cathepsins / Cyclohexanes / Amides / Aminoacetonitrile Limits: Animals Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2006 Document type: Article

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