Novel indole inhibitors of IMPDH from fragments: synthesis and initial structure-activity relationships.

Beevers, Rebekah E; Buckley, George M; Davies, Natasha; Fraser, Joanne L; Galvin, Francis C; Hannah, Duncan R; Haughan, Alan F; Jenkins, Kerry; Mack, Stephen R; Pitt, William R; Ratcliffe, Andrew J; Richard, Marianna D; Sabin, Verity; Sharpe, Andrew; Williams, Sophie C

Beevers, Rebekah E; Buckley, George M; Davies, Natasha; Fraser, Joanne L; Galvin, Francis C; Hannah, Duncan R; Haughan, Alan F; Jenkins, Kerry; Mack, Stephen R; Pitt, William R; Ratcliffe, Andrew J; Richard, Marianna D; Sabin, Verity; Sharpe, Andrew; Williams, Sophie C.

Affiliation

Beevers RE; UCB Celltech, Granta Park, Great Abington, Cambridge, CB1 6GS, UK.

Bioorg Med Chem Lett ; 16(9): 2539-42, 2006 May 01.

Article in En | MEDLINE | ID: mdl-16483773

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Collection: 01-internacional Database: MEDLINE Main subject: Enzyme Inhibitors / IMP Dehydrogenase / Indoles Limits: Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2006 Document type: Article Affiliation country: Reino Unido Country of publication: Reino Unido

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