HIV-1 Group N: evidence of ongoing transmission in Cameroon.
AIDS Res Hum Retroviruses
; 22(5): 453-7, 2006 May.
Article
in En
| MEDLINE
| ID: mdl-16706623
ABSTRACT
An HIV-1 group N infection, 02CM-DJO0135, was identified among specimens collected in 2002 at the D'Joungolo Hospital, Yaoundé, Cameroon. Sequences were obtained from viral RNA extracted from plasma for regions of LTR-gag, pol-vif, and env. The virus amplified from the specimen is closely related to a previously reported group N virus, 02CM-DJO0131, that was also collected at this hospital in 2002. Although the viral sequences for the two isolates differ, their close relationship suggests that the two specimens are linked. No patient histories are available for 02CM-DJO0131 and 02CM-DJO0135; the specimens could have been drawn from a husband/wife, mother/child, or a single individual. However, differences in seroreactivity indicate that it is unlikely that the specimens were drawn from the same patient. This report documents the second case that suggests linkage between group N-infected individuals and indicates that there is ongoing transmission of HIV-1 group N in Cameroon.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
RNA, Viral
/
HIV Infections
/
HIV-1
Type of study:
Prognostic_studies
Limits:
Humans
Country/Region as subject:
Africa
Language:
En
Journal:
AIDS Res Hum Retroviruses
Journal subject:
SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS)
Year:
2006
Document type:
Article
Affiliation country:
Estados Unidos