Ubiquitous MyoD transcription at the midblastula transition precedes induction-dependent MyoD expression in presumptive mesoderm of X. laevis.
Cell
; 65(6): 927-37, 1991 Jun 14.
Article
in En
| MEDLINE
| ID: mdl-1675156
ABSTRACT
We have used a quantitative reverse transcription-polymerase chain reaction assay to detect MyoD mRNA during early embryonic development of Xenopus laevis. We find that during a short period of time following the midblastula transition MyoD becomes transcriptionally activated at a low level ubiquitously throughout the embryo. Restriction of MyoD expression to muscle precursor cells appears as a subsequent event, in which the process of mesoderm induction stabilizes transcription only in the marginal zone of the embryo, the presumptive mesoderm.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Xenopus laevis
/
Muscle Proteins
Limits:
Animals
Language:
En
Journal:
Cell
Year:
1991
Document type:
Article