Endophthalmitis after open globe injury: microbiologic spectrum and susceptibilities of isolates.
Am J Ophthalmol
; 142(5): 852-4, 2006 Nov.
Article
in En
| MEDLINE
| ID: mdl-17056367
ABSTRACT
PURPOSE:
To present the microbiologic spectrum and susceptibilities of isolates in posttraumatic endophthalmitis, and to provide a review of the literature.DESIGN:
Retrospective consecutive case series.METHODS:
A review of 1182 consecutive open globe injuries was performed, identifying 10 patients with culture-proven endophthalmitis.RESULTS:
Thirteen organisms were isolated from 10 eyes with posttraumatic endophthalmitis. Isolated organisms included Streptococcus species (46.2%), coagulase-negative Staphylococcus (23.1%), and Bacillus cereus (15.4%). All organisms tested were susceptible to vancomycin and tobramycin. The most commonly isolated organisms from an aggregate posttraumatic endophthalmitis pool of 372 cases obtained by literature-based meta-analysis were coagulase-negative Staphylococcus (21.5%) and Bacillus cereus (18.5%).CONCLUSION:
We report a high prevalence of gram-positive pathogens and a notable prevalence of Bacillus cereus in posttraumatic endophthalmitis. Susceptibility results suggest that posttraumatic endophthalmitis isolates are generally susceptible to vancomycin and tobramycin.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Bacteria
/
Eye Infections, Bacterial
/
Eye Injuries, Penetrating
/
Endophthalmitis
Type of study:
Observational_studies
/
Risk_factors_studies
Limits:
Humans
Language:
En
Journal:
Am J Ophthalmol
Year:
2006
Document type:
Article
Affiliation country:
Estados Unidos