Strategies for adapting automated seizure detection algorithms.
Med Eng Phys
; 29(8): 895-909, 2007 Oct.
Article
in En
| MEDLINE
| ID: mdl-17097325
ABSTRACT
The time-varying dynamics of epileptic seizures and the high inter-individual variability make their detection difficult. Osorio et al. [Osorio, I, Frei, MG, Wilkinson, SB. Real-time automated detection and quantitative analysis of seizures and short-term prediction of clinical onset. Epilepsia 1998;39(6)615-27] developed an algorithm that has had success in detecting seizures. We present a new strategy for adapting this algorithm or other algorithms to an individual's seizure fingerprint using both seizure and non-seizure training segments and a novel performance criterion that directly incorporates the non-linearity and lack of differentiability of the algorithm. The joint optimization of a linear filter chosen from a bank of candidate filters and of a percentile used in order statistic filtering provides an empirical solution that is both practical and useful, which should translate into improved sensitivity, specificity and detection speed. This premise is strongly supported by the results obtained in a large validation study and the examples illustrated in this article. This strategy is generalizable to other detection algorithms with modular architecture and spectral filters.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Seizures
/
Algorithms
/
Artificial Intelligence
/
Diagnosis, Computer-Assisted
/
Electroencephalography
Type of study:
Diagnostic_studies
/
Evaluation_studies
/
Prognostic_studies
Limits:
Humans
Language:
En
Journal:
Med Eng Phys
Journal subject:
BIOFISICA
/
ENGENHARIA BIOMEDICA
Year:
2007
Document type:
Article
Affiliation country:
Estados Unidos