Erosive arthropathy: clinical variance in lupus erythematosus and association with anti-CCP case series and review of the literature.
Clin Exp Rheumatol
; 25(1): 47-53, 2007.
Article
in En
| MEDLINE
| ID: mdl-17417990
ABSTRACT
OBJECTIVE:
To describe the occurrence of erosive arthropathy in systemic lupus erythematosus (SLE) and its relationship to anti-CCP antibodies.METHODS:
Retrospective medical record review of a case series of five female patients with SLE and erosive arthropathies.RESULTS:
The initial disease presentation in all patients was a polyarthritis. Anti-CCP antibodies were detected in 4 out of 5 (80%) patients, 2 of whom had a positive rheumatoid factor.CONCLUSION:
Erosive arthritis was strongly associated with the presence of anti-CCP antibodies in these patients with SLE, who presented with polyarthritis. Anti-CCP in patients with SLE may be a marker of a more severe joint disease.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Peptides, Cyclic
/
Arthritis, Rheumatoid
/
Hand Joints
/
Lupus Erythematosus, Systemic
Type of study:
Etiology_studies
/
Risk_factors_studies
Limits:
Adult
/
Female
/
Humans
/
Middle aged
Language:
En
Journal:
Clin Exp Rheumatol
Year:
2007
Document type:
Article
Affiliation country:
Colombia