The L80I substitution in the reverse transcriptase domain of the hepatitis B virus polymerase is associated with lamivudine resistance and enhanced viral replication in vitro.
Antimicrob Agents Chemother
; 51(7): 2285-92, 2007 Jul.
Article
in En
| MEDLINE
| ID: mdl-17438047
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Virus Replication
/
Hepatitis B virus
/
Reverse Transcriptase Inhibitors
/
Lamivudine
/
Drug Resistance, Viral
/
DNA-Directed DNA Polymerase
Type of study:
Risk_factors_studies
Limits:
Humans
Language:
En
Journal:
Antimicrob Agents Chemother
Year:
2007
Document type:
Article
Affiliation country:
Australia