Early bactericidal activity of high-dose rifampin in patients with pulmonary tuberculosis evidenced by positive sputum smears.
Antimicrob Agents Chemother
; 51(8): 2994-6, 2007 Aug.
Article
in En
| MEDLINE
| ID: mdl-17517849
ABSTRACT
We studied the early bactericidal activity of twice the standard dose of rifampin in subjects with pulmonary tuberculosis evidenced by positive smears. The observed mean 2-day activity was almost double that reported at the standard dose. Further studies are warranted to establish whether higher rifampin doses might assist in shortening tuberculosis treatment.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Rifampin
/
Sputum
/
Tuberculosis, Pulmonary
/
Mycobacterium tuberculosis
/
Antitubercular Agents
Limits:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
Language:
En
Journal:
Antimicrob Agents Chemother
Year:
2007
Document type:
Article
Affiliation country:
Sudáfrica