Variation in fasting and non-fasting serum enterolactone concentrations in women of the Malmö Diet and Cancer cohort.
Eur J Clin Nutr
; 62(8): 1005-9, 2008 Aug.
Article
in En
| MEDLINE
| ID: mdl-17538540
ABSTRACT
OBJECTIVES:
The aim of this study was to examine the variation of enterolactone from fasting and non-fasting blood of middle-aged healthy women eating a normal diet to determine the usefulness of a single sample in epidemiological studies. SUBJECTS ANDMETHODS:
Twenty-six women born between 1940 and 1950 were recruited within the Malmö Diet and Cancer cohort. Three non-fasting and two overnight fasting samples were collected from each individual during a 5-week period. Twenty-one participated in all measurements. Enterolactone concentrations were analyzed by time-resolved fluoroimmunoassay.RESULTS:
The within-subject and between-subject variations (coefficient of variations, CV) were estimated to 59 and 89% respectively for fasting samples and 71 and 67% for non-fasting samples. The intraclass correlation coefficients (ICC) were estimated to 0.66 (95% confidence interval (CI) 0.35-0.84) for fasting and 0.48 (95% CI, 0.22-0.72) for non-fasting samples.CONCLUSIONS:
Although the estimated ICC for blood samples was moderate, it indicates that enterolactone levels of both fasting and non-fasting blood samples should be useful in future projects within the Malmö Diet and Cancer cohort.
Search on Google
Collection:
01-internacional
Database:
MEDLINE
Main subject:
4-Butyrolactone
/
Fasting
/
Lignans
/
Postprandial Period
/
Phytoestrogens
Type of study:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Risk_factors_studies
Limits:
Female
/
Humans
/
Middle aged
Language:
En
Journal:
Eur J Clin Nutr
Journal subject:
CIENCIAS DA NUTRICAO
Year:
2008
Document type:
Article
Affiliation country:
Suecia